Phytochemicals and cancer

Phytochemicals and cancer.

Epidemiological studies showing a protective effect of diets rich in fruits and vegetables against cancer have focused attention on the possibility that biologically-active plant secondary metabolites exert anti-carcinogenic activity. This huge group of compounds, now collectively termed 'phytochemicals', provides much of the flavour and colour of edible plants and the beverages derived from th...

Phytochemicals and Cancer – Possible Molecular Targets of Phytochemicals in Cancer Prevention and Therapy

Phytochemicals in Cancer Prevention and Therapy.

1Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, KY 40536, USA 2Cell Dynamics Research Center and School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Republic of Korea 3Breast Cancer Program, School of Medicine, Johns Hopkins University, Baltimore, MD 21231, USA 4Division of Cancer and Stem Cell Biology...

Cancer therapy with phytochemicals: evidence from clinical studies

Cancer is still one of the major causes of mortality in both developing and developed countries. At this time, in spite of intensive interventions, a large number of patients have poor prognosis. Therefore, the effort for finding new anticancer agents with better efficacy and lesser side effects has continued. According to the traditional recommendations and experimental studies, numerous medic...

Phytochemicals in the treatment of ovarian cancer.

Ovarian cancer ranks 5th among the most common gynecologic cancers and causes the highest mortality in females. Here, we discuss the role of a group of natural products that are being used in treatment and prevention of a host of cancers including ovarian cancer. Some plants and nutraceuticals and their polyphenolic constituents such as flavones, flavonoids, and antioxidants have shown cytotoxi...